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Denmark's Zealand Pharma and Boehringer Ingelheim said their experimental obesity treatment achieved up to 14.9% weight loss in a mid-stage trial, lining up a potential contestant in the booming obesity drug market. In a statement on Wednesday (May 10), the partners said that the Phase II dose-finding trial met its primary endpoint of weight loss after 46 weeks. Paola Casarosa, head of therapeutic areas at Germany's Boehringer Ingelheim told Reuters the partners are in discussion with regulators about the design of a planned follow-up trial in the third and last phase of testing. The enormous demand for weight-loss treatments such as Novo Nordisk's Wegovy, or potentially Eli Lilly's Mounjaro, could support as many as 10 competing products with annual sales reaching up to $100 billion within a decade, mostly in the United States, industry executives and analysts said. Lilly said about a year ago that Mounjaro was shown to reduce up to 22.5% in weight after 72 weeks of treatment in a much larger late-stage trial.

It might be actresses such as Suzanne Sommers and Jane Fonda, or models such as Christie Brinkley or Kathy Ireland. It seems that a number of celebrities today offer their own weight loss programs. The programs are appealing because we see these various svelte celebrities and we want to have bodies just like them. The celebrities are also highly likable, so we have a predisposition to be accepting of their products. However, did you ever stop to think whether these celebrities have any nutritional training? Do they have medical training? Is the information that they offer nutritionally sound? Or is it just a good sales pitch? Nutrition experts Annette B. Natow and Jo-Ann Heslin, authors of the book Get Skinny the Smart Way, say that consumers should be leery of celebrity-inspired diet books. They point out that such books are often based upon nutritional fiction and that, while the diets outlined in these books may result in short-term weight loss, they can be far from healthy in the long run. Therefore, you might consider passing up the celebrity diet books and opting for those written by nutritional experts instead. But celebrities aren't the only ones preaching fad diets. For instance, there's the so-called grapefruit diet which recommends consuming a grapefruit prior to each meal. Another fad is the cabbage soup diet, which requires you to consume all the cabbage soup you can handle. Other fads call for eating all the eggs you can…consuming only raw foods…or fasting every other day. Such diets are not only based on nutritional misinformation-they can also be dangerous. For instance, let's take a closer look at the cabbage soup diet. No major health organization has endorsed it. Moreover, the American Heart Association disapproves of it, noting that it can actually harm you. Promoters of this diet say that you can lose as much as 15 pounds a week by following it-what they don't say is that mos

Metabolic training exercises have been found to be ideal for hastening calorie burn resulting in rapid fat loss. A raised metabolism lets us achieve significant fat loss with less physical effort which can only mean shorter, more effective workouts.

New data on weight loss drugs that could compete with Novo Nordisk's Wegovy are raising expectations there will soon be more options, and possibly lower prices, in an estimated $100 billion marketplace, doctors and pharmaceutical executives say. Drugmakers are ratcheting up their research and aiming for new formulations that can be taken as pills, options to deliver higher weight loss or drugs that reduce fat while maintaining muscle. "It has really been an explosion of innovation," said Dr. Robert Gabbay, chief science officer at the American Diabetes Association (ADA), which receives funding from both Novo and Eli Lilly and Co and just concluded its annual meeting in San Diego, California. "If there are multiple (treatments) in the market, that will lead to some level of competition and greater access."

Computer Science Tuesday, April 25, 2023 Computer hardware Computer hardware is the physical components that make up a computer system. It includes everything from the central processing unit (CPU) to the monitor, keyboard, and mouse. Understanding the different types of hardware and how they work together is essential for anyone who works with computers. In this article, we will explore the various components of computer hardware, including internal and external components, and the peripherals that connect to them. We will also discuss the importance of hardware maintenance, the latest advancements in computer technology, and factors to consider when choosing the right hardware for your needs. Whether you are a computer technician, a gamer, or simply someone who uses a computer for everyday tasks, this article will help you better understand the world of computer hardware. Introduction to Computer Hardware Computer hardware refers to the physical components that make up a computer system. It includes everything from the processor and memory to input/output devices such as the keyboard and monitor. In this article, we will explore the different types of computer hardware and their functions. What is Computer Hardware Computer hardware refers to the physical components of a computer system. It includes all the components that can be touched, seen, and used to interact with a computer, such as the monitor, keyboard, and mouse. Hardware is different from computer software, which refers to the programs and applications that run on a computer system. History of Computer Hardware The history of computer hardware dates back to the 1820s when Charles Babbage, an English mathematician, and inventor, designed the first analytical engine, which was considered to be the first mechanical computer. With time, more complex electronic computers were developed, including the first Intel microprocessor in 1971. Since then, computer hardware has continued to evolve, becoming

"How can I tone my body at home when I don't have time?" While gym equipment might be great, nobody has enough time to go to the gym every day, these days. It is the digital era; or you could say the era of DIY, (do it yourself), memes and GIFs. Busy schedules have led to increased demand for online and in-home services. Urban Clap, Swiggy, Zomato, Uber Eats, are few popular examples of such. The latest trend is the no-equipment home workout. So how to get a perfectly toned body at home? Read on to know how to tone up loose skin, how to tone your muscles and overall, how to tone your body at home. But First, What is Body Toning? Body toning is basically a fine-tuning fitter and a better physique with primary emphasis on the musculature. Few may want to tone to simply look better, some may be fitness enthusiasts, some may just wish to carve their bodies for a defined, muscular shape. Toning also helps to tighten loose skin, reduce stretch marks after weight loss or weight gain. Though sometimes used interchangeably with "gymming", toning is also associated with simpler, external forms of a workout than hardcore workouts. How Long Does it Take to See Results from Workout? An average person takes about 6-8 weeks to begin noticing significant results. However, a regular and intense practitioner may begin to notice changes by 4-5 weeks. And for the body types that show slow results, it might take about 12 weeks to view significant positive changes. Diet plays a very crucial role in the entire process and can have a drastic impact on the results. Another factor that affects the results is the original weight of the person. Needless to mention, the more the weight, the more time it will take, and vice versa. DIY: How Do I Tone My Body - With This Simple 10 Min Workout For any of the below exercises, the maximum space you would require is to be able to take 4-5 long steps. A good warm-up session is crucial before an actual workout. Then switch to these eas

There are several benefits to losing weight, including higher self-esteem, better mood, improved sleep pattern, and better health in general. In addition, you can prevent various health concerns associated with obesity, such as heart problems and diabetes. There are different ways to help reduce weight, including lifestyle changes. It requires discipline, perseverance, and commitment to reach your goal and maintain it. The first step to making these changes can be challenging, but you must push yourself and keep moving forward to achieve your objective. If you are a beginner, the weight loss tips can be overwhelming, and some may be too hard to do that it could demotivate you or make you give up. So, we listed some tips for losing weight that are ideal for beginners. Set your goal Although you may want to lose weight immediately, the truth is that it will not happen overnight. Remember that it did not take one day to gain all those extra pounds, so you cannot lose them instantly. Setting your expectations straight is essential, so you won't be disappointed if you do not see an immediate result. You need consistency to be where you want to be, so make sure you have a clear objective. You can set smaller goals that you can achieve within a shorter period, then set another goal after that until you reach your ideal weight. You will feel motivated by these small wins, making you want to keep going.

Every year we make new resolutions about getting healthier. But at the middle of the first month of the New Year, we lose our motivation and interest towards exercising. Losing weight is every one's dream. However, only few of us stay in shape. Others just curse them and get distracted. In fact, they start making new plans. So, let us take a quick look at the weight loss routine of a passionate and consistent health enthusiast. First Tip: Exercising is not a joke. If you choose a set of exercises that are too much for your present physical condition then you could end up in the hospital. In fact, something worse can happen too. So, preparing a list of exercises before trying them is a wise idea. You can also ask for help from a professional in this regard. An expert can teach you to perform best weight loss exercises. Second Tip: Drink lot's of water. The trick to drinking water is simple not keeping drinks in the refrigerator full of sugar. You will be surprised of the weight that you will lose by substituting water for drinks.

The National Pharmacy Association (NPA) has raised the alarm that many community pharmacies are facing losses on NHS prescriptions due to the "broken" funding system. An analysis of prescription drug prices by the NPA revealed that pharmacies are being underpaid by the NHS by up to £75 a pack for common medicines, resulting in losses of thousands of pounds each month. The analysis report released today (16 October) shows the government reimburses £18.06 for a 56-tablet pack of Amantadine, a drug used to treat Parkinson's symptoms. However, the market price of the drug is £94.05 per pack, leading to a loss of £75.99 per 56-tablet pack for pharmacies-amounting to a shortfall of over £1 per tablet. In some instances, NHS funding covers only one-fifth of the cost that pharmacies have to pay for medicines, according to new figures from the NPA.

You are overweight for the most simple of reasons -- because you're eating the wrong foods, the wrong types of calories per meal, and you're also eating meals in the wrong patterns each day.Think closely about what we're about to tell you, since it's going to change the way you think about dieting...FOOD is more powerful than any prescription weight loss pills, because the FOOD that you eat can either make you THIN or FAT. You don't get fat because of a lack of exercising, that's a myth. You get fat because you don't eat the right foods at the right intervals each day.Also, the pattern that you choose to eat your meals each day is more powerful than any prescription weight loss pills. This is true because your body is like an 'engine' and it only needs certain foods at certain intervals each day, and if you don't eat the right foods at the right times then it won't burn those calories -- and you'll wind up storing those calories as fat tissue. (Hint: You need to eat more than 3 times per day to lose weight, but we'll show you the details later).Don't want to wait for details later. Go now and see this amazing 'diet'!Click Here

You guys could start to cycling for losing weight in a healthy way. Here is how you could know how to begin: https://ababike.com/how-to-start-cycling-when-overweight/

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Is Customized Fat Loss a SCAM? The bespoken Fat Loss program has steady gained quality within the weight loss and fitness world since its unleash a handful of months back. this can be beyond any doubt a nice surprise for Kyle Leon, author of the program, given the very fact that the majority fitness enthusiasts and dieters alike area unit sometimes skeptical regarding fresh free diet programs, like the Custom Fat Loss program. Like its name suggests, the system was designed around individualistic nutritionary desires that area unit bespoken to specific user needs. this can be wherever the overwhelming majority of diet programs out there fail. They merely don't cater to users' distinctive nutritionary desires. Whereas bespoken Fat Loss could be a comparatively new program on the fasting and fitness scene, Kyle Leon himself isn't new. He's splendidly attributable for leading the manner within the field of bespoken fasting and fitness guides once he free an analogous program known as the Somanabolic Muscle Maximizer that caters to the distinctive dietary desires of body builders. ..... http://customizedfatlosstips.blogspot.com/

One of our contributing experts recently put together a kick-butt article that is the "Do This - and DON'T Do That" rule-book when it comes to getting rid of unsightly cellulite dimples, shadows and ripples. It's a quick read with some eye-opening tips and a helpful video that you'll want to see while it's still up. http://listofsymulastexercises.blogspot.com/

Are you cycling to lose weight. Maybe you have just taken up the sport or perhaps come back to it after many years absence. In this article you will learn how many calories you are burning when you cycle. You will also learn how to structure your cycling time to achieve weight loss goals.

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In leptitox diet program, you will discover that there is a hormone called Leptin that controls our hunger and food cravings. When fat cells start growing, they will release a hormone called Leptin. This is what controls how hungry you feel. When you have a low level of leptin, you feel hungry. When you have high levels of this hormone, you feel full. With this, you can easily fall into what is called "leptin resistance" where you can quite get to the point you feel full, so you keep eating. Leptin has significantly increased in the past decades....click link for more

Trimulean provides you a support for lifetime, helping you in achieving your weight loss goals and maintaining optimum health through a natural process and that is why it is being considered as the best alternative to natural dietary supplements.

The Green Coffee Weight Loss Program is combined with an exciting new breakthrough ingredient that comes with a complete online comprehensive diet and weight loss program to help you lose weight. Combined with a sensible food program, exercise routine, and drinking plenty of water, the program will help you to regain your slim body easier and faster. Affiliates earn up to $75 per sale!

Weight loss journeys are hard no matter where you start or how far you have come. At some point, most people have tried to lose weight and ended up quitting due to plateauing or receiving improper guidance. There are also seemingly endless weight lo…

When someone says erectile dysfunction, the first thing that you may think is of "Viagra" or similar drugs to revive your sex crusade. Even if established medics can assist, they induce side effects, which is why most men choose natural options. Besides, adverse effects of Viagra can result in back pain, memory issues, nausea, loss of hearing, and more. When shifting to natural remedies, you can improve your sexual version without giving the body a ridiculous amount of toxins and chemicals. Ginger, a root vegetable and one of the main ingredients in many traditional Asian dishes, has been used for centuries in conventional medications to treat various ailments. In recent years, ginger has received attention as an herbal remedy for sexual health problems such as erectile dysfunction (ED), premature ejaculation (PE), and infertility. It turns out that this ancient herb can be very effective at improving your sex life! How Does Ginger Benefits Male Sexually? Its potent medicinal combinations have made this natural treatment a focal point in investigations and comprehensive research over the years. Here is what makes ginger (zingiber officinale) a mighty sexual therapy. We've enclosed all the benefits it can suggest. But, nothing has gained more momentum than its impact on male sexual ability. 1. Ginger is an aphrodisiac and boosts sex drive. Ginger has been used as an aphrodisiac for centuries. An aphrodisiac is any food or medicine that stimulates sexual intuition, cajoles veneral craving, and boosts pleasure and performance. The spicy flavor of ginger can help increase your libido and has also been shown to improve erectile dysfunction and sexual performance in men. Aside from its role as an aphrodisiac, ginger is also a known sperm motility enhancer. In fact, according to clinical studies, just one gram of fresh ginger can improve sperm count by up to 35 percent! 2. It can improve sexual satisfaction. Ginger can also improve overall sexual satisfaction by

Many community pharmacies are under severe financial strain due to chronic underfunding and a mismatch between medicine costs and reimbursement rates. A report by the National Pharmacy Association (NPA) revealed that NHS underpays pharmacies by up to £75 a pack for common medicines, resulting in losses of thousands of pounds each month. The NPA analysis found that, in many instances, NHS funding covers only one-fifth of their purchase costs for medicines. Nemesh Patel, Managing Director of the Southdowns Pharmacy Group, said the current pharmacy funding contract is "completely broken and beyond farcical." Sharing their struggles, he tells Pharmacy Business: "Our teams are wasting hours and hours trying to just source medication for patients when they could be better using that time to clinically support our patients, and then when it comes to reimbursement, the drug tariff prices or concessionary prices are structured such that on hundreds of medications we dispense per month, we will be making a significant financial loss, each and every single time our pharmacies dispense that medication."